DNA-guided CRISPR–Cas12a effectors DNA-guided CRISPR–Cas12a effectors for programmable RNA recognition and cleavage

2026-07-22
조회수 44
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🧬 A paradigm shift in CRISPR diagnostics — and MIRA is part of it.
For years, crRNA was considered essential for Cas12a function.
Not anymore.
A recent Nature Biotechnology study has redefined the rules:
🔬 The breakthrough: Single-stranded crDNA can independently guide Cas12a for precise RNA targeting — decoupling activation from sequence recognition. This completely overturns the long-held assumption that crRNA is indispensable.
⚡ Why it matters: This discovery not only rewrites the CRISPR-Cas12a mechanism but also paves the way for simpler, more cost-effective diagnostic platforms.
🤝 And here's the key: The system is perfectly compatible with MIRA technology from AMP-FUTURE BIOTECH — enabling a stable, low-cost, highly specific integrated RNA detection platform for point-of-care testing.
From crRNA-dependence to DNA-guided independence.
From lab-only to field-ready.
This is the future of CRISPR molecular diagnostics — and we're proud that MIRA is at its core. 🧬

1. MIRAmp DNA Basic Kit, 48T
2. MIRAmp RNA Basic Kit, 48T
1. LbCas12a Nuclease, 200pmol, 2000pmol, 10,000pmol
2. LwaCas13a Nuclease, 200pmol, 2000pmol, 10,000pmol
제품 주문 및 문의 : biotools@icloud.com